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4 In comparison, when Fe 3+ was bound to the MnSOD protein, the specific activity was about 140 units/mg

Since the orthotopic injection site provides the murine stromal support and an environment most similar to the site of the human tumor, it is generally preferred over the heterotopic sites (58)

However, that is not the whole picture

Advanced immunosuppression is a known risk factor and even single episode of pneumonia is associated with increased morbidity and mortality [6]
