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Evaluating URAT1 inhibitors in wild-type mice is practically futile

Consult your healthcare provider to discuss its benefits and suitability for your condition

Ice crystal formation denatures the peptide irreversibly Unreconstituted powder (lyophilized): - Store in the freezer at -20 degrees Celsius for maximum shelf life (months to years) - Refrigerated storage at 2 to 8 degrees Celsius is acceptable for several months - Room temperature tolerance: 2 to 4 weeks without significant degradation - Keep the desiccant packet in the container to absorb moisture Practical storage tips: - Store vials on a middle shelf of the refrigerator, not in the door

In the context of radiotherapy, hypoxic tumor cells exhibit increased resistance due to their impaired ability to produce damaging oxygen radicals upon irradiation (94)