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Description
J.KalacskaM.MackenzieS
[PMID: 9802174] 3
Sphingolipid dysregulation within lipid rafts near podocyte slit diaphragms contributes to cytoskeletal rearrangement, oxidative stress, and inflammation (66, 102)
This study not only validates the feasibility of the mitochondrial dysfunction-induced cell death strategy, but also demonstrates the translational potential of biomimetic drug delivery systems in metabolism-targeted therapy
