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doi: 10.1097/01.pas.0000162762.03068.7a
SevcsikE.PabstG.RichterW.DannerS.AmenitschH.LohnerK.2008Interaction of LL-37 with Model Membrane Systems of Different Complexity: Influence of the Lipid Matrix
The solvent-exchange-mediated aggregation mechanism allows injection through needles as small as 30 G (with no polymer) and 25 G (with a low amount of polymer excipient) while extending the drug release timeframe relative to aqueous suspensions by promoting structural integrity and minimizing surface area via microcrystal compaction
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