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Bilirubin Heme oxygenase-1 (HO-1) is the enzyme that generates carbon monoxide, iron, and biliverdin using the heme fraction as a substrate [39], and biliverdin reductase that reduces biliverdin to bilirubin being this molecule the ending product of the heme degradation

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3.Measure the dosage accurately to avoid overdosing or underdosing

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Tan Z, et al

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10.2147/DMSO.S106087 183 XieZ.HeC.ZouM

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