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These data confirm the important role of TREK-1 and TRAAK in CIPN [82, 83]
Distribution Channel Analysis 5.5
This effect was enabled by activating the p75NTR and TrkA receptors and the upstream MAP/ERK signaling pathway
Thus, treatment of LNCaP cells with the DNA demethylating agent 5-azacytidine also restored activating histone modifications on GSTP1 and as a result reactivated transcription
