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Kim MN, Moon JH, Cho YM

Because of its low molecular mass and lipophilic characteristics, this molecule may easily pass across the bloodbrain barrier (BBB) 3

In cell culture models of human macrophage foam cells, the inability to clear cholesterol from macrophages with compromised lysosome function continues even in the presence of compounds that stimulate efflux (161,163)

Thus, the S-nitroso-acetyl-lipoate modification likely represents S-nitrosation occurring after the enzyme is inhibited at the acetylated state
