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Neurogenesis and widespread forebrain migration of distinct GABAergic neurons from the postnatal subventricular zone

Two major authoritative assessments synthesized these findings: the U.S

Ricciardi MR, Konopleva M, Ruvolo P, McQueen T, Milella M, Sneed T, Andreeff M

These include ~50 gene loci, with mutations in three Mendelian genes myocilin (MYOC), optineurin (OPTN) and TANK binding kinase (TBK1) accounting for ~5% of POAG cases with little influence from other genes or environmental factors (12, 20)