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Its important to note that early detection and treatment of Vitamin B-12 deficiency is vital because if left untreated, the deficiency can cause severe neurologic problems and blood diseases

PRESCRIPTIVE B12 VERSUS NON PRESCRIPTIVE B12 PRESCRIPTION B12 Hydroxocobalamin NICE-recommended form used by the NHS Prescribed by a GMC or NMC-registered medical practitioner Medical consultation required your safety is assessed first Same clinical standard as your GP Longer-lasting and more stable in the body No cyanide content Administered by a qualified medical professional using correct technique Monitored and reviewed protocol adjusted to your individual needs Private blood testing available to confirm deficiency and track response Legal, compliant and fully documented prescription NON-PRESCRIPTION B12 Often cyanocobalamin cheaper synthetic form not recommended by NICE Not prescribed no prescriber involved No medical consultation or safety assessment required Not the same standard as your GP Shorter-acting and less stable Contains a small amount of cyanide the body must detoxify Administered by non-medical staff with no clinical oversight No monitoring, no review, no adjusted protocol No blood testing deficiency not confirmed No legal prescription grey area of compliance VITAMIN B12 FAQS Vitamin B12 Injection FAQs What is the difference between hydroxocobalamin and cyanocobalamin

Considering that the Hedgehog pathway is implicated in the initiation and maintenance of PAAD [82] and NNMT is a potential downstream target gene of Hedgehog, the elevation of NNMT level in PAAD may be a result of the continuously activated Hedgehog signaling pathway

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