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10.1097/MIB.0000000000001109 [DOI] [PubMed] [Google Scholar] 28

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Free Radic Res 2000

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431 SOS acts as a GEF, and the binding of the GRB2-SOS complex to Ras facilitates the transition of the inactive form of Ras (Ras-GDP complex) to an active state (Ras-GTP complex) within the cell membrane

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Collectively, these findings propose that sAH might be the result of both impaired hepatocyte regeneration and immunopathology

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