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Protandim supplementation prevented the loss of endothelium-dependent vasodilation in response to acetylcholine (ACh) in middle cerebral arteries (MCA) of HS-fed rats and hamster cheek pouch arterioles, and increased microvessel density in the cremaster muscle of HS-fed rats

Otherwise, the assay should be repeated until acceptance criteria are met

Neurogenic inflammation encompasses hyperemia, plasma protein extravasation, mediator release, and leukocyte infiltration and has been thought to contribute to a series of inflammatory diseases, including asthma and COPD

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