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Once translocated to the nucleus, NF-B activates RelA (p65) via phosphorylation, promoting the transcription of key components of the NLRP3 inflammasome, including NLRP3, ASC, and caspase-1

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doi: 10.1038/bjc.2011.254 36 BlanckHMMarcusMTolbertPERubinCHendersonAKHertzbergVSet al

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The term "theranostics" defines the ongoing efforts in the clinic to combine diagnostic and therapeutic capabilities in a single pharmaceutical agent [96]

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Cytokine quantification was performed by ELISA (IL-6, BD Biosciences, 555240

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