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Phenotypes such as sensitivity to ozone, salinity, high light, photo-inhibition, accelerated senescence and others may reflect compensatory mechanisms of the mitochondrial respiration in response to endogenous low AsA synthesis rather than the lack of AsA-antioxidant capacity

PubMed, Huang, Lu-Wen, et al

Ethics statement The studies involving humans were approved by Italian Ministry of Health (MoH) PNRR-MCNT2-2023-12377707

This was investigated in the present clinical trial of 83 patients, randomised to the bumetanide group (bumetanide treatment, 0.5 mg twice daily) or the control group (no bumetanide treatment)