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Our results suggest that CBS of the TSS pathway plays an important role in maintaining cysteine levels under restricted cystine availability or excess hemin exposure, and CBS upregulation by DMF increases the cellular glutathione levels to protect against ROS and ferroptosis stress in SCD

Genetic and chemical modification of selected BNPs Following the pioneering works of Finn, Johnson and Francis, our group has further explored the surface functionalization of BNPs with genetic and chemical methods