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Abstract Rheumatoid arthritis (RA) is a chronic, progressive, and systemic inflammatory autoimmune disease, characterized by synovial inflammation, synovial lining hyperplasia and inflammatory cell infiltration, autoantibody production, and cartilage/bone destruction

It is hoped that the central role of the intestinal epithelium in this regulation will become more evident

A study in Cu-exposed Silene cucubalus demonstrated increased lipid peroxidation and a more oxidized GSSG/GSH ratio after Cu treatment (20 M)