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As noted in this study, the complex action of BPC 157 tends to rule out a simple effect of either the vasoconstrictor (L-NAME) or the vasodilator (L-arginine)[3] in the noted rapid presentation of blood vessels that bypass the two obstructions of major vessels and reestablishing the blood flow that was interrupted by ligation in rats which subjected to the ischemic colitis procedure

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TB-500 also suppresses the NF-kB inflammatory pathway systemically, not just locally

Notably, research into chicken embryos suggests a probable mechanism through which BPC-157 works: It appears to initiate the activation of a receptor called VEGFR2