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Description
Based on the modeled PDZD-8 structure, we hypothesized that changing leucine-98 and isoleucine-252 of the PDZD-8 SMP domain to tryptophan (W) would block lipid insertion into its hydrophobic groove (Supplementary Fig
[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Scafidi S, OBrien J, Hopkins I, Robertson C, Fiskum G, McKenna M
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J Clin Investig
