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Ovarian histology (follicle counts, fibrosis) and biochemical parameters (hormones, inflammatory and oxidative markers) were assessed

Besides its role in the delivery of nutrients, it helps to rehydrate the body, restoring electrolyte balance and aiding cellular function

Transcription of ARE results in the production of numerous antioxidant enzymes, such as SOD, GPx, glutathione-s-transferase(GSTr), catalase (CAT), heme-oxygenase-1 (HO-1), NADPH-quinone-oxidoreductase (NQO-1), phase II enzymes of drug metabolism and heat shock proteins (HSP)

BBB also restricts entry of neuro-therapeutic drugs and hinders treatment modalities