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Image 1: Cellular metabolism of various forms of vitamin B12 Image: Simplified depiction of the metabolism of various forms of vitamin B12 supplements in the cytosol

In addition, the absence of resistance of peptides to breakdown by gastrointestinal proteolytic enzymes (e.g., carboxypeptidases or aminopeptidases) should be mentioned [8], which in practice precludes administrating such a drug to the patient orally and calls for intravenous administration

Your body needs this vitamin to produce red blood cells and synthesize DNA, according to the NIH

ICH Q3C provides a framework for residual-solvent risk classification in pharmaceutical contexts