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Stallings VA, Stark LJ, Robinson KA et al (2008) Evidence-based practice recommendations for nutrition-related management of children and adults with cystic fibrosis and pancreatic insufficiency: results of a systematic review

Additional contributions come from enzymes such as xanthine oxidase and cyclooxygenases, as well as endoplasmic reticulum stress and unfolded protein response activation, which further exacerbate oxidative stress through disrupted calcium homeostasis and oxidative signaling pathways (Fig

therefore, signal/background provides good sensitivity