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Many cases of obesity are characterized by faulty hormonal signals, insulin resistance, chronic inflammation, dysregulated satiety response, altered gut-brain axis signaling, and metabolic adaptation

In recent decades, calcium channel blockers and modulators of mitochondrial dynamics, such as mitochondrial division inhibitor 1 (Mdivi-1) and the mitochondrial fusion promoter M1, have demonstrated cardioprotective and neuroprotective properties in various experimental models [129, 135, 136]

Other causes of agitation seen after a head injury may include pain, depression, infection, side effects of medications, sleep deprivation, or electrolyte imbalance

Hofstetter W, Swisher SG, Correa AM, Hess K, Putnam JB, Ajani JA, Dolormente M, Francisco R, Komaki RR, Lara A, Martin F, Rice DC , Sarabia AJ, Smythe WR, Vaporciyan AA, Walsh GL, Roth JA
