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In some parts of China (e.g., Keshan), the intake was only 314 g/day (56, 57), and the endemic Se deficiency appeared in the form of chronic osteochondropathy (KashinBeck disease) and chronic cardiomyopathy (Keshan disease), which are now preventable through Se supplementation (71, 72)

De Couck M, Nijs J, Gidron Y (2014) You may need a nerve to treat pain: the neurobiological rationale for vagal nerve activation in pain management

Antioxidants role is to eliminate free radicals, terminate chain reactions, and inhibit further oxidative reactions, while they themselves are oxidized ( Antioxidants are abundant in daily life, with major sources including endogenously synthesized antioxidants, such as water-soluble and lipid-soluble antioxidants and antioxidative enzymes;natural antioxidants from food, such as various types of flavonoids, flavanols, anthocyanins, etc

Meanwhile, new potential peptide drugs are being discovered,24 suggesting promising but as-yet-undetermined directions in the treatment of common health concerns
