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When germ-free mice were exposed to constraint stress, they exhibited a stronger stress response compared to normal mice, with significant increases in adrenocorticoid and glucocorticoid levels

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The effect of acute or chronic oral NAC to improve GSH in tissues including the liver, kidneys, skin, and brain has been evaluated in several animal models of physiologic and pathologic conditions [66]

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Lamson DW, Brignall MS

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IV drip therapy is far more effective than oral supplements

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