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doi: 10.1210/jcem.83.4.4744 136 MaccarioMVeldhuisJDBroglioFVitoLDArvatEDeghenghiRet al
As a novel inhibitor of nicotinamide N-methyltransferase (NNMT), 5-amino-1mq has shown broad application prospects in anti-aging studies
Key finding: NNMT positioned as a master metabolic regulator at the intersection of NAD+ salvage, one-carbon metabolism, and epigenetic control
Poor lipid metabolism is often associated with conditions like insulin resistance[8], which can lead to increased fat storage and difficulty maintaining a healthy weight
