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Description
As an ectoenzyme, CD38 catalyzes conversion of NAD + to nicotinamide, which is then almost completely reused for NAD + synthesis via the salvage pathway (Fig
(2) Kopchick JJ, Berryman DE, Puri V, Lee KY, Jorgensen JOL
In other cancers, CD38 is mainly expressed by cells in the tumor microenvironment
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