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This is contrary to the past century of thinking about bilirubin being a toxic bile substance that causes liver dysfunction and the yellowing of the skin in jaundice

Findings in this regard point toward increased social anxiety (43, 44, 48, 54), potentially mediated by the role of DHEA and DHEAS in responses to social stress (46, 58), potentially to facilitate adaptive stress responses in the context of increasing social and emotional demands (64, 65)

Biochim Biophys Acta 1817:13141321 Cha JY, Barman DN, Kim MG, Kim WY (2015) Stress defense mechanisms of NADPH-dependent thioredoxin reductases (NTRs) in plants