igf-1 lr3 side effects joint pain Therapy Improves Muscle Size and Function in Experimental Peripheral Arterial Disease Targeting IGF1/IGF1r signaling relieve pain
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[DOI] [PubMed] [Google Scholar] 82.Natanzon Y., Goode E.L., Cunningham J.M

Hepatology 1994

doi: 10.1016/j.neuron.2007.11.026
Over time, this may lead to downregulation of GH receptors, impaired signaling, and diminished therapeutic effect
