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[DOI] [PubMed] [Google Scholar] 8.Messiaen LM, Callens T, Mortier G, Beysen D, Vandenbroucke I, Van Roy N, et al

Sermorelin is often preferred for long-term anti-aging protocols because: Its gentle, physiological GH stimulation is sustainable over months to years Lower risk of GH-related side effects with extended use Better preservation of the pituitarys natural feedback mechanisms Supports collagen production, skin quality, and tissue repair without excessive hormone exposure CJC-1295 may be preferred when anti-aging goals overlap with body composition concerns or when a patient has not responded adequately to sermorelin alone

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Under pathological conditions, microgliaas a function of different stimuliare activated to exert neuroprotective effects (M2 phenotype) or to release inflammatory factors and neurotoxic substances (M1 phenotype)