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To address this knowledge gap, here we develop a mathematical model that incorporates the most essential molecular elements for NADPH production, ROS generation, GSH synthesis, and detoxification of ROS by GSH in the outer retina, formed by photoreceptors and the RPE (see Fig
M., Smith, R
p21 exerts this anti-apoptotic function through several key mechanisms, predominantly when localized in the cytoplasm
The chemistry of enzyme and protein immobilization with glutaraldehyde
