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With the exception of E220D in Lineage 5, these SNPs occur close to the tips of the phylogenetic tree affecting only one or a few isolates and suggesting that they are of relatively recent origin
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Likewise, during activity the mean decrease in pain score was 11.69 mm/h (95%CI 10.10-13.28 mm/h) for indomethacin and 11.38 mm/h (95%CI 9.98-12.79 mm/h) for prednisolone
