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Consequently, increasing the activity of phase II enzymes, such as glutathione S-transferases (GSTs) and NQO-1, may help prevent cancer by enhancing the elimination of potential carcinogens (see the Nrf2-dependent antioxidant pathway) (63)

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Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer

Developmental Pb 2+ exposure has also been linked to increased apoptosis, particularly during critical periods of brain formation, contributing to long-term neurodevelopmental abnormalities in both mammalian and zebrafish models [75]