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Description
require documentation of indication, dosing, and clinical response Biologics (IL-12/23 inhibitor): Ustekinumab (Stelara, J3357) FDA-approved for moderate-to-severe CD
Lee et al., 2004
Thus, three types of animal models are widely employed for modeling the different aspects of MS: (1) Virus-induced demyelination, (2) Experimental autoimmune encephalomyelitis (EAE), and (3) toxin provoked demyelination [12, 13]
For example, B12 uptake by the gut commensal Bacteroides thetaiotaomicron was shown in vitro to limit the production of Shiga toxin-2 produced by enterohemorrhagic Escherichia coli O157:H7 (EHEC) [12]
