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Senescence was induced in the cells via doxorubicin treatment (40 nM) then resuspended in DMEM prior to injection

Soy isoflavones reduced the number of atretic follicles, lowered caspase-3 and ROS levels, and increased Bcl-2 and total antioxidant capacity (TAC) levels in naturally aged rats, which may be related to their involvement in antioxidant and anti-apoptotic processes in ovarian tissues (147)

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