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Iron ions are becoming accessible in the pre-membrane space during the process of oxidation and denaturation of membrane-bound hemoglobin occurring with aging of RBC (Low et al., 1985)

Experimental studies in animal models and study of the mutant proteins in cultured cells suggest that the defective proteins encoded by these genes cause cataracts by interfering with the normal function of lens fiber cells or by promoting their own aggregation and, perhaps, the aggregation of normal lens proteins

DOI: Article Snippet: Patient derived T cells were isolated from B-ALL patients and cultured in lymphocyte medium KBM581 (Corning, USA) supplemented with 10% FBS and 50 IU/mL human interleukin-2 (IL-2) (R&D systems, USA). Qiao, Y., Chen, J., Wang, X., Yan, S., Tan, J., Xia, B., Chen, Y., Lin, K., Zou, F., Liu, B., He, X., Zhang, Y., Zhang, X., Zhang, H., Wu, X., & Lu, L

Comparisons between trial arms used similar methods
