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The issue of poor bioavailability was recently circumvented with the development and introduction of a novel glutathione that aids in gastrointestinal uptake [31]

doi: 10.1016/j.fct.2019.111047 55 MostDFergusonLHarrisRA

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In this setting, CYB5R3 functions not only as a preserver of hemoglobin activity but also as a responsive regulatory valve controlling NO signaling within RBCs