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Furthermore, Treg cells require the phosphoinositide 3-kinase (PI3K)-mTORC2 pathway to induce expression of the glycolytic enzyme glucokinase [160]

Metformin boosts antitumor immunity and improves prognosis in upfront resected pancreatic cancer: an observational study

doi: 10.1007/s00392-022-02129-5

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