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Glutathione Peroxidase (Gpx) Gpx is a tetrameric selenoprotein that catalyzes the detoxification of H 2 O 2 (reaction 6) and lipid peroxides (reaction 7) by reducing glutathione (GSH), mainly in the mitochondria but also in the cytosol, playing a key role in the protection of cells from oxidative damage by inhibiting lipid oxidation
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This suggests that TCM can be used to intervene in AMD by adjusting the intestinal flora, increasing SCFAs and BAs, and ameliorating oxidative damage, apoptosis, inflammation, and altered choroidal hemodynamics
