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Figure 1 Patients with GSSD, which is classified as mild, moderate, or severe based on clinical symptoms, usually show disease onset symptoms during the neonatal period ( 2
GSH is also essential for the glyoxalase system, which contributes to the detoxification of reactive dialdehydes and is utilized during protein glutathionylation, which is a crucial step in the post-translational regulation of protein metabolism (97)
The MBI behavior of MDMA on CYP2D6 implies that subjects, irrespective of their genotype/phenotype, are phenocopied to the poor metabolizer (PM) phenotype
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