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Induction of favismlike symptoms in the rat: Effects of vicine and divicine in normal and buthionine sulphoximinetreated rats

This review aims to deepen the understanding of ferroptosis mechanisms and advance the clinical application of regulatory therapies for OA

6.4 Ferroptosis and pyroptosis Pyroptosis, also known as cellular inflammatory necrosis, is programmed cell death induced by activation of inflammatory vesicles and is mainly regulated by cysteinyl asparagine-1, -4, -5, and -11-dependent signaling pathways (Teng et al., 2023)