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Besides, ACSL1 is recently found essential for -eleostearic acid (ESA) induced ferroptosis

For each cell type, CpGs exhibiting a statistically significant difference, defined by a false discovery rate (FDR) less than 0.05, were identified as cell type-specific DMCs

The high heterogeneity of HNSCC, including differences in HPV status, primary tumor sites, driver gene mutation profiles, and tumor microenvironment heterogeneity, leads to significant inter-individual variations in treatment response, making the traditional one-size-fits-all therapeutic model ineffective

Having two distinct methods (i.e., the GNPT-coatomer interaction and the LYSET-GOLPH3 interaction) for recycling GNPT at the Golgi and a third to retrieve any escaped enzyme ensures the robustness of the M6P pathway, minimizing the risk of its compromise