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Explanation of Discomfort and Pain Management Laser tattoo removal can cause some discomfort, often described by patients as similar to being snapped by a rubber band or experiencing hot specks on the skin

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During oncogenic transformation of hematopoietic cells, chromatin-bound CDK6 phosphorylates NFY and SP1 transcription-factors and induces expression of p53-antagonists such as PRMT5, PPM1D and MDM4 (42)
