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The NMDAR hypofunction leads to cortical oxidative stress, GSH deficiency, and decreased activity of the thioredoxin/peroxiredoxin system through transcriptional control of several critical antioxidant genes [24]

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Key components of an ADC include a tumour-targeting antibody, a cytotoxic drug and a linker connect-ing the antibody to the cytotoxic drug (Table 3)

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