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Prevalence and Outcomes of Anemia and Hematinic Deficiencies in Patients With Chronic Heart Failure

Although OxS is a consequence of normal body and organ physiology, severely impaired oxidative homeostasis results in DNA hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells function and viability

Vitamin C acts as an antioxidant which help to assist with collagen formation

The intrinsic pathway is triggered by diverse intracellular stresses, such as DNA damage, metabolic perturbations, or endoplasmic reticulum stress, leading to mitochondrial outer membrane permeabilization (MOMP)