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The human deletion is better modelled by Df1/ + mice, which carry a heterozygous deletion of 27 orthologs of del22q11.2 genes, 9 of which are involved in metabolic processes, including 5 that are involved in mitochondrial activity

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Breakpoint: Based on pharmacokinetic studies of enrofloxacin in dogs and cats after a single oral administration of 2.5 mg enrofloxacin/kg BW (i.e