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To read more on this, see our article: Vitamin B Complex

There is no prospective evidence above 2.4 mg weekly, so pushing higher is not a useful plateau strategy

It binds to glycine receptors in the spinal cord and brainstem, producing calming effects
Roux-en-Y gastric bypass surgery (RYGB) but not sleeve gastric bypass surgery or gastric banding, increases the risk of vitamin B 12 deficiency and requires preventive post-operative treatment with either injected or high-dose oral supplementation
