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Kaludercic, N., Deshwal, S
They found that, compared with healthy controls, FMS sufferers had lower levels of CoQ10 and ATP, increased oxidative stress, inflammation and mitochondrial dysfunction, which were to some extent explained by changes in gene expression
After infectious or sterile stimuli, SLC15A4 in DCs is recruited to phagosomes, SLC15A4deficient DCs infected with Salmonella typhimurium show reduced caspase-1 cleavage and IL-1 production, this correlates with peripheral NLRC4 inflammasome assembly and increased autophagy
Roy, S., Jaiswar, A
