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The pungency of Garlic: activation of TRPA1 and TRPV1 in response to allicin

[DOI] [PubMed] [Google Scholar] 54.Zhang Z, et al

282 Mechanistically, this might occur via the downregulation of TJ-related mRNA expression (e.g., occludin, CLDN1/3/4, and ZO-1)

The mainly vesicular intracellular localization of MRP1 in STB and pFECs was puzzling given the fact that these drug transporters are generally considered to be cell surface localized and to mediate drug resistance by lowering total intracellular drug concentrations
