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3fg, both WT and GCGR-KO cells exhibited rapid calcium influx responses, but the frequency and magnitude of cytoplasmic Ca 2+ concentration oscillations were notably more pronounced in GCGR-KO cells
Nevertheless, there is evidence that a high expression of c-Met in HCC is related to a poor prognosis (Rimassa et al., 2016)
Therefore, triptolide demonstrates versatile anti-cancer effects across various cancer types, highlighting its potential as a promising therapeutic agent with broad-spectrum activity against tumors
Key mechanisms include DNA methylation, histone modifications, and non-coding RNA-mediated regulations (Fig
