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Induction of ferroptosis through inhibition of glutathione peroxidase 4 (GPX4) GPX4 plays a critical role in the cellular peroxidase system, inhibiting the formation of peroxides and thus acting as a key regulator of ferroptosis

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The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine

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& Handler, P

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The pathological changes of blue light damage to the ocular surface, crystalline lens, and retina mentioned above may lead to various eye diseases, such as keratitis, dry eye syndrome, cataracts, myopia, and age-related macular degeneration (Figure 1)

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