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THC is distributed and metabolized in a region-specific manner, with highest levels in the hippocampus
(2022) 119:e2121987119
doi: 10.1128/JB.01655-07 177 ZhouE.SeminaraA
In order to further confirm that PXR is an upstream regulator for MDM2, we transfected siRNA targeting PXR, and the results showed that PXR knockdown resulted in downregulation of ATF3 and upregulation of MDM2 ( Figure 5H , lane 2 vs
